This paper introduces an image-driven audio-visual universal source separation (ID-USS) and proposes ID-USS-Conformer. ID-USS aims to separate a target source from the mixture based on the input image that is consistent with the target. Importantly, ID-USS only focuses on the sound made by the target in this image, not on the description of the target or the semantic information of the picture. In detail, ID-USS-Conformer mainly consists of an Efficient-b3-based visual branch and a Conformer-based audio branch. The visual branch extracts the visual clue of the target from the input image. After the audio branch fuses the visual features, ID-USS-Conformer separates the target source from the mixture. We launch an ID-USS dataset and verify the effectiveness of ID-USS-Conformer on it. The ID-USS-Conformer has achieved a 10.139 dB signal-to-distortion ratio improvement in the test set and outperformed the compared methods.