A framework for joint source/channel coding of speech is presented. It is based on a harmonic representation of the speech signal and facilitates efficient quantization of harmonic amplitudes and phases both in a single description and a multiple description setting. Furthermore, it combines high-quality packet loss concealment with efficient source coding and multiple description coding. Two proof-of-concept codecs are presented; a single description codec that is equivalent to iLBC in terms of bitrate and quality but more robust in conditions of increased packet losses and a multiple description codec that is capable of accepting loss rates up to 40% for a DCR score of 3.8.