A number of real-life speech applications using BSS have been reported for two channel applications but only a few have been reported for multi-channel (more than 2 channels) applications. Moreover these mostly involve simulation studies or real-life separations in controlled settings. In this paper some practical problems of multichannel applications will be analyzed. A methodology is proposed to bypass the full fledged higher dimensional BSS problem by exploiting the relative spatial arrangement of microphones to achieve improved speech enhancement by selective 2-channel BSS. The concept is illustrated on a 3 source / 3 microphone setup in speech recognition experiments involving an acoustic scene with a human speaker and interferring noise sources.