The aim of the Computer Aided Learning Enhancement project (CALE) at the University of Hertfordshire is to provide a totally hands-free interface to a PC based computer system, for use by disabled school children. The project focusses on two major aspects - firstly the provision of a human centred, appropriately customised system designed to compensate for manual disability, and secondly the enhancement of the learning process and consequent improvement in skills resulting from the introduction of the interface into the learning environment. This paper deals with the latter aspect, drawing directly on examples from a particular case study.